Designs for Health OmegAvail TG 1000™ 120 softgel caps

Polyunsaturated fatty acids are comprised of two groups of essential fatty acids, omega-6’s (linoleic acid) and omega-3’s (alpha-linoleic acid), with the latter, subsequently converting to eicosapentaenoic (EPA) and docosahexaenoic acid (DHA). They are classified as essential because the rate of EPA and DHA biosynthesis from ALA is very low (8% and 1% respectively), consequently maintaining optimal endogenous levels to effectively support physiological functional processes requires regular intake from dietary sources. However, a broad body of evidence confirms that in many Western countries, intake of EPA and DHA across many sub-population groups is inadequate. This is a consequence of both inadequate omega-3 intake and excessive omega-6 consumption. EPA and DHA are also classified as essential because of the many important physiological functions they are involved in, including supporting heart health, brain and cardiovascular function.

Two vital factors to consider when ingesting therapeutic quantities of omega-3 fatty acids is purity and environmental impact. Extracted using urea technology, OmegAvail TG1000™ has superior oxidation parameters. It also has exceptional environmental parameters, being sustainably certified by IFFO Global Standard for Responsible for Supply and Friend of the Sea

A significant body of evidence has demonstrated an association between endogenous levels of EPA and DHA and cardiovascular health, which is attributed to a significant number of cardioprotective mechanisms of actions that omega-3 fatty acids are involved in.  Such mechanisms include antioxidant, antiplatelet, promoting healthy blood lipid levels, cell membrane and vascular endothelial function, as well as reducing pro-inflammatory mediator concentrations (eicosanoids, prostaglandins, leukotrienes, and resolvins).

This has translated into clinically relevant outcomes, with findings from a broad body of evidence demonstrating a dose-dependent beneficial effect of omega-3 supplementation for improving cardiovascular health as measured by several clinical and biological endpoint subtypes

The brain is highly concentrated in omega-3 fatty acids, and optimal levels are necessary for normal brain, structure, function and health at all life stages. Specific mechanisms omega-3 fatty acids are involved that support healthy brain function includes being a key cell membrane component, promoting optimal membrane fluidity, neurogenesis, intracellular signalling, synaptic transmission and repair processes, as well as inhibiting pro-inflammatory mediator-driven neuroinflammation. Clinical evidence demonstrates a beneficial effect of omega-3 supplementation in young and middle-aged adults and older individuals. A comprehensive systematic review found that in young adults, omega-3 supplementation improved endogenous fatty acid profiles, reading abilities (phonologic decoding time and visual analysis time) and also enhanced neurocognitive function. Improvements observed in middle-aged adults included enhanced memory functionality and brain structure (white matter microstructural integrity and grey matter volume), while in older individuals omega-3 supplements protected against neurodegeneration.

Adults: Take 1-2 capsules per day or as directed by your healthcare practitioner